TY - JOUR A1 - Sinha, Pallavi A1 - Singh, Lavleen A1 - Dhingra, Dhulika T1 - Congenital tuberculosis: A diagnosis delayed in a child with atrial septal defect Y1 - 2020/1/1 JF - Annals of Tropical Pathology JO - Ann Trop Pathol SP - 79 EP - 81 VL - 11 IS - 1 UR - https://www.atpjournal.org/article.asp?issn=2251-0060;year=2020;volume=11;issue=1;spage=79;epage=81;aulast=Sinha DO - 10.4103/atp.atp_42_19 N2 - Congenital tuberculosis (CTB) is a rare disease presenting in infants with very few cases reported despite a high burden of tuberculosis. The fewer reported cases reflect in part the difficulty in making a definitive clinical diagnosis as signs and symptoms are non- specific along with difficult laboratory confirmation due to several reasons. We report a case of 4-month-old male child presenting with fever and cough for 3 months and respiratory distress and feeding difficulties for 5 days with no response to antibiotics. Systemic examination revealed bilateral crepitations, pansystolic murmur, and hepatosplenomegaly. Echocardiography revealed an 8 mm atrial septal defect. The patient did not respond to decongestive therapy. Ultrasonography revealed an enlarged liver with a 12 cm liver span. Liver biopsy showed necrotizing epithelioid cell granuloma. Based on the Cantwell's criteria, the diagnosis of CTB was proffered. ER -