RT - Journal TY - JOUR A1 - Oduyebo, O A1 - Olayinka, A A1 - Iregbu, K A1 - Versporten, A A1 - Goossens, H A1 - Nwajiobi-Princewill, P A1 - Jimoh, O A1 - Ige, T A1 - Aigbe, A A1 - Ola-Bello, O A1 - Aboderin, A A1 - Ogunsola, F T1 - A point prevalence survey of antimicrobial prescribing in four Nigerian Tertiary Hospitals YR - 2017/1/1 JF - Annals of Tropical Pathology JO - Ann Trop Pathol SP - 42 OP - 46 VO - 8 IS - 1 UL - https://www.atpjournal.org/article.asp?issn=2251-0060;year=2017;volume=8;issue=1;spage=42;epage=46;aulast=Oduyebo;t=5 DO - 10.4103/atp.atp_38_17 N2 - Introduction: Antimicrobial resistance has become a global challenge in health care. Its emergence in previously sensitive bacteria is usually associated with poor antibiotic-prescribing patterns. Methodology: A point prevalence survey was carried out in four tertiary hospitals in Nigeria in 2015 to determine the rate and characteristics of antibiotic prescription. Results: Of 828 patients eligible for the study, 69.7% received antibiotics, with highest rates in the adult Intensive Care Unit. There were therapeutic indications in 51.2% of the prescriptions, of which 89.5% were for community-acquired infections. Third-generation cephalosporins were the most prescribed antibiotics. On the evaluation of surgical prophylaxis, only 4.1% were compliant with institutional guidelines and 39.2% gave a reason for prescribing in patient case notes. Less than 1% of the prescriptions were based on the use of biomarkers. Conclusion: The prevalence of antibiotic prescription in Nigerian hospitals is high with only about 50% of prescriptions based on clear therapeutic indications. We provide evidence that the country needs to institute a cohesive antimicrobial stewardship intervention program. ER -