%A Oduyebo, O
%A Olayinka, A
%A Iregbu, K
%A Versporten, A
%A Goossens, H
%A Nwajiobi-Princewill, P
%A Jimoh, O
%A Ige, T
%A Aigbe, A
%A Ola-Bello, O
%A Aboderin, A
%A Ogunsola, F
%T A point prevalence survey of antimicrobial prescribing in four Nigerian Tertiary Hospitals
%9 Original Article
%D 2017
%J Annals of Tropical Pathology
%R 10.4103/atp.atp_38_17
%P 42-46
%V 8
%N 1
%U https://www.atpjournal.org/article.asp?issn=2251-0060;year=2017;volume=8;issue=1;spage=42;epage=46;aulast=Oduyebo
%8 January 1, 2017
%X Introduction: Antimicrobial resistance has become a global challenge in health care. Its emergence in previously sensitive bacteria is usually associated with poor antibiotic-prescribing patterns. Methodology: A point prevalence survey was carried out in four tertiary hospitals in Nigeria in 2015 to determine the rate and characteristics of antibiotic prescription. Results: Of 828 patients eligible for the study, 69.7% received antibiotics, with highest rates in the adult Intensive Care Unit. There were therapeutic indications in 51.2% of the prescriptions, of which 89.5% were for community-acquired infections. Third-generation cephalosporins were the most prescribed antibiotics. On the evaluation of surgical prophylaxis, only 4.1% were compliant with institutional guidelines and 39.2% gave a reason for prescribing in patient case notes. Less than 1% of the prescriptions were based on the use of biomarkers. Conclusion: The prevalence of antibiotic prescription in Nigerian hospitals is high with only about 50% of prescriptions based on clear therapeutic indications. We provide evidence that the country needs to institute a cohesive antimicrobial stewardship intervention program.
%0 Journal Article
%I Wolters Kluwer Medknow Publications
%@ 2251-0060