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Year : 2017  |  Volume : 8  |  Issue : 2  |  Page : 75-80

Derivation of a list of priority antibodies from the analysis of a cohort of cases sent from Nigeria for external consultation

1 Department of Cellular Pathology, Queen's Hospital, Romford, England, United Kingdom
2 Department of Morbid Anatomy, University of Nigeria Teaching Hospital, Enugu State, Nigeria
3 Department of Anatomic and Molecular Pathology, Lagos University Teaching Hospital, Idi-Araba, Lagos, Nigeria

Correspondence Address:
Dr. D B Olusina
Department of Morbid Anatomy, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu, Enugu State
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/atp.atp_10_17

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Introduction: The major obstacle to developing sustainable services in a resource-limited setting, which hitherto has not had routine availability of diagnostic immunohistochemistry (IHC), is choosing from a large array of over 200 antibodies that are currently in use in the Western world. Materials and Methods: By critically analyzing the use of diagnostic IHC in a cohort of 360 cases sent for consultation from Nigeria to the UK between January 2014 and May 2016, we have derived a list of antibodies that could meet over 85% of current diagnostic IHC needs in Nigeria. Results: From our analysis, a starter list of only two antibodies could immediately meet over 30% of the IHC needs. Having mastered this starter list, the service could move to the next step by adding 23 other antibodies which could meet another 85% of diagnostic IHC needs. Conclusions: Testing with these 25 antibodies can be done at least twice weekly to address the 3 areas mentioned above and greatly increase the chances of success in establishing a sustainable service. We recommend this list to the various groups working with diagnostic IHC in Nigeria and look forward to reports of their efforts.

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