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Year : 2012  |  Volume : 3  |  Issue : 2  |  Page : 139-141

Alteration of ABH blood group antigens in a patient with acute leukaemia

Department of Haematology, University College Hospital (UCH), Ibadan, Nigeria

Correspondence Address:
T Kotila
Department of Haematology, University College Hospital, PMB 5116, Ibadan
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Source of Support: None, Conflict of Interest: None

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The loss or weakening of an individual's blood group due to disease is a rare phenomenon, which occurs more with myeloid malignancies. We report here the loss of the A antigen in an 18 year old boy treated for acute lymphoblastic leukaemia with a combination of Cyclophosphomide, Oncovin, Cytosine Arabinoside and predisolone. At first hospital admission he was typed as AB RhD positive but four months later he was typed as B RhD positive.

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