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CASE REPORT
Year : 2019  |  Volume : 10  |  Issue : 2  |  Page : 159-162

Myeloid sarcoma presenting with proptosis, ruptured globe, and facial swelling


1 Department of Paediatrics, Ahmadu Bello University, Ahmadu Bello University Teaching Hospital, Shika-Zaria, Kaduna State, Nigeria
2 Department of Histopathology, Ahmadu Bello University, Ahmadu Bello University Teaching Hospital, Shika-Zaria, Kaduna State, Nigeria
3 Department of Haematology and Blood Transfusion, Ahmadu Bello University, Ahmadu Bello University Teaching Hospital, Shika-Zaria, Kaduna State, Nigeria

Correspondence Address:
Dr. Jamilu Abdullahi Faruk
Department of Paediatrics, Ahmadu Bello University Teaching Hospital, P.M.B 06, Shika-Zaria, Kaduna State
Nigeria
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/atp.atp_23_19

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Myeloid sarcoma (MS) is a rare malignancy of immature myeloid cells and/or monocytes that occur in an extramedullary site. It is frequently mistaken for small-round-blue cell tumors, in the absence of immunohistochemistry. A case report of an unusual presentation of MS with a ruptured globe at a tertiary setting of North-western Nigeria is presented. The patient was a 12-year-old girl with progressive bilateral proptosis and spontaneous rupture of the left eye. A histologic diagnosis of embryonal rhabdomyosarcoma was made, but she had a minimal improvement in her clinical condition following chemotherapy. Further review showed bone marrow myeloblasts >98%. The previous tissue biopsy was subjected to immunohistochemistry and found to be CD117 – strongly positive and CD34 – patchy positive. The conclusion was that of myeloid leukemic infiltration of orbital tissue MS. The patient abandoned the treatment due to caregiver fatigue and financial exhaustion.


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