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ORIGINAL ARTICLE
Year : 2019  |  Volume : 10  |  Issue : 2  |  Page : 119-121

The total antioxidant status and antioxidant vitamins in Gombe, Nigeria


1 Department of Chemical Pathology, College of Medical Sciences, Gombe State University and Federal Teaching Hospital, Gombe, Nigeria
2 Department of Chemical Pathology, University of Ibadan, University College Hospital, Ibadan, Nigeria
3 Department of Chemical Pathology, Ahmadu Bello University, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria
4 Department of Community Medicine, College of Medical Sciences, Gombe State University and Federal Teaching Hospital, Gombe, Nigeria

Correspondence Address:
S Adamu
Department of Chemical Pathology, Gombe State University, Gombe
Nigeria
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/atp.atp_13_19

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Background: Measuring individual oxidants and antioxidants as markers of oxidative stress may be expensive, time-consuming, and open to a great deal of errors. In addition to freedom from the above, total antioxidant status (TAS) combines the synergistic effects of all the antioxidants in the system including those yet to be discovered. Aims and Objectives: The aim of this study was to evaluate the correlation between plasma levels of antioxidant vitamins (Vitamins A, C, and E) and TAS in Gombe, Nigeria. Materials and Methods: Pearson's correlation was used to correlate between plasma levels of antioxidant vitamins (Vitamins A, C, and E) and TAS among 180 people. Antioxidant vitamins (Vitamins A, C, and E) were analyzed using high-performance liquid chromatography and TAS was analyzed using standard colorimetric methods. Results: The mean age of the participants is 29.14 ± 3.6 years, and the mean body mass index is 23.26 ± 3.1. There was a significant strong (P < 0.001) positive correlation between TAS and Vitamin A (r = 0.59), Vitamin E (r = 0.52), and Vitamin C (r = 0.62). Conclusion: This study has demonstrated a high level of correlation between plasma levels of antioxidant vitamins (Vitamins A, C, and E) and TAS. This is an indication that TAS may assume a clinical status as a marker of oxidative stress. It may reduce the number of analytes, cost, time, and errors involved in assessing individual oxidants and antioxidants as markers of oxidative stress.


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